Synovea® HR (Hexylresorcinol)

Synovea® HR (Hexylresorcinol)

Hexylresorcinol is an organic compound traditionally found in mouthwashes with local anaesthetic, antiseptic and anthelmintic properties.

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It is available for use topically on small skin infections, or as an ingredient in throat lozenges. Johnson & Johnson markets hexylresorcinol in its Neutrogena and RoC skincare products as an anti-aging cream.

Recently, however, its ability to target pathways in the skin that lead to hyperpigmentation has propelled it into the skin lightening ingredient category. There is also thought that Hexylresorcinol has more benefits as well, including an ability to reduce the appearance of fine lines and wrinkles, increase protection against UVB and UVA rays, and improve the skin’s barrier against pollution and sun exposure.

Clarins and other top brands in cosmetics have also introduced a serum that lightens dark spots while firming the skin.

Complexi-Light research team has decided to use Synovea HR from Sytheon as their source for hexylresorcinol. With safety, performance, differentiation and stability with the four key value drivers and with strong claim substantiation and with similar core values, alliance with Sytheon to create Complexi-Light has been vital in this formulation. Sytheon develops and offers a wide range of scientifically and clinically validated ingredients for improving health and beauty of the skin. Sytheon provides innovative solutions in areas such as of aging of skin and pigmentation control. Sytheon has several publications and issues and pending European and US patents.

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in vitro

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Synovea® HR and Asyntra® SL Inhibiting Multiple Sites in the Melanogenesis Pathway

Synovea® HR is modulating at least eight sites in the melanogenesis pathway:

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